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These Insights might not exist for you but could exist for those who constructed this Disease X-19 Pandemic – M.N.
“No scientist or group of scientists created this virus in a laboratory. That would require insight into [viral] pathogenesis and protein engineering that does not exist,” said Robert Garry, Ph.D., virologist at Tulane University.
|Michael Novakhov – SharedNewsLinks|
|Virologists vigorously debunk new study on origins of the novel coronavirus – ABC News|
|Genomic epidemiology of SARS-CoV-2 spread in Scotland highlights the role of European travel in COVID-19 emergence | medRxiv|
Abstract SARS-CoV-2, the causative agent of COVID-19, emerged in Wuhan, China in December 2019 and spread rapidly throughout the world. Understanding the introductions of this new coronavirus in different settings may assist control efforts and the establishment of frameworks to support rapid response in future infectious disease outbreaks. We investigated the first four weeks of emergence of the SARS-CoV-2 virus in Scotland after the first case reported on the 1st March 2020. We obtained full genome sequences from 452 individuals with a laboratory-confirmed diagnosis of COVID-19, representing 20% of all cases until 1st April 2020 (n=2310). This permitted a genomic epidemiology approach to study the introductions and spread of the SARS-2 virus in Scotland. From combined phylogenetic and epidemiological analysis, we estimated at least 113 introductions of SARS-CoV-2 into Scotland during this period. Clusters containing multiple sequences suggestive of onward transmission occurred in 48/86 (56%). 42/86 (51%) clusters had no known international travel history indicating undetected introductions. The majority of viral sequences were most closely related to those circulating in other European countries, including Italy, Austria and Spain. Travel-associated introductions of SARS-CoV-2 into Scotland predated travel restrictions in the UK and other European countries. The first local transmission occurred three days after the first case. A shift from travel-associated to sustained community transmission was apparent after only 11 days. Undetected introductions occurred prior to the first known case of COVID-19. Earlier travel restrictions and quarantine measures might have resulted in fewer introductions into Scotland, thereby reducing the number of cases and the subsequent burden on health services. The high number of introductions and transmission rates were likely to have impacted on national contact tracing efforts. Our results also demonstrate that local real-time genomic epidemiology can be used to monitor transmission clusters and facilitate control efforts to restrict the spread of COVID-19.
|WHO clarifies comments on asymptomatic spread of coronavirus: ‘There’s much unknown’|
… about how often people can spread the coronavirus when they do not have symptoms. … But it may boil down to how one defines “asymptomatic.” …
|Coronavirus Could Have Been in Wuhan in August 2019, According to Harvard Study|
A pre-print article published by Harvard University suggests that trends in hospital traffic and search engine data from the Chinese province of Wuhan in late Summer and early fall 2019 could be attributed to SARS-CoV-2.1
The emergence of SARS-CoV-2, the virus that has caused the COVID-19 pandemic, was initially linked to the Huanan Seafood Market in Wuhan, China in late November – early December 2019. However, the authors of the article highlight that there are a few disparities surrounding this. Firstly, research which linked two-thirds of the identified coronavirus cases to the Huanan Seafood Market failed to find a direct connection to the market for 14 of the cases including the first case. Subsequently, the door is left open as to the point of origin and infection. 2,3,4
Secondly, analysis of the wildlife in the Huanan market could not be linked to SARS-CoV-2, implying that transmission of the virus could have occurred downstream from the spill over event when a virus “spills over” from one species to another. 2,3,4
In the article, Nsoesie et al describe how these disparities led them to consider the idea that SARS-CoV-2 could actually have been circulating in Wuhan prior to its linking to the market.
Previously, digital epidemiology and non-traditional data streams have proven valuable tools in respiratory disease surveillance, including internet search trends. As such, the researchers adopted this method to further explore a potential alternative origin of SARS-CoV-2.
In the study, they adopted vehicle counts extracted from satellite imagery of hospital parking lots in Wuhan to estimate trends in hospital occupancy and explored this in association with reported illnesses linked to influenza.
They also used Baidu search trends the Chinese technology company specializing in internet-related services to analyze the searches of disease related terms.
Increased number of hospital visits
Michael Novakhov – SharedNewsLinks℠